Achiratidza 1-12 pamusoro 36 zvabuda

HAKASI HERE. PRODUCT NAME MASHOKO ANOBATA NYAYA
    935881-37-1 AR-42 (935881-37-1)

    AR-42 inoratidzira HDAC inhibitor, inoratidzira biologic basa rinopesana nemaronda ane mast cell lines through down-regulation of constitutively activated ...

    844442-38-2 AT7519 (844442-38-2)

    AT7519 inhibitor ye multiple cyclin-dependent kinases (CDKs), izvo zvinogona kuita kuti sero rinenge rakasungwa, kuiswa kwe apoptosis, uye inhibi ...

    602306-29-6 AZD5438 (602306-29-6)

    AZD5438 inhibitor yakasimba yeCDK1 / 2 / 9 ne IC50 ye16 nM / 6 nM / 20 nM. Hazvikwanisi kuCDK5 / 6 uye inhibits GSK3β. Phase 1.

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    865783-99-9 Briciclib (865783-99-9)

    Briciclib ibhenyl styryl sulfone analog, uye eyediumdium phosphate ester prodrug ye ON 013100, ine basa rinogona kushandiswa nemasikirini.

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    1421693-22-2 CDKI-73 (1421693-22-2)

    CDKI-73 yakawanda CDK9 inhibitor neChi ye 4 nM. Inoratidzira tsvina yeCLL cells (LD50 = 80 nM) zvichienderana nechechi B chetendi uye yeCD34 yakazara ...

    199986-75-9 CVT-313 (NG-26) (199986-75-9)

    CVT-313 yakasimba, yakasarudzwa, yakashandurwa, uye ATP-inokwikwidza inhibitor yeCDK2 (IC50 = 0.5 M yeCdk2 / A uye Cdk2 / E; 4.2 M yeCdk1 / B; 21 ...

    779353-01-4 Dinaciclib (SCH727965) (779353-01-4)

    Dinaciclib (SCH727965) inoyevedza uye yakawanda CDK inhibitor yeCDK2, CDK5, CDK1 uye CDK9 ne IC50 ye1 nM, 1 nM, 3 nM uye 4 nM, maererano ...

    942918-07-2 GSK1070916 (942918-07-2)

    GSK1070916 inoshamisa Aurora B / C kinase inhibitor (ine IC50 ye3.5 nM / 6.5 nM) ine basa rinoparadzanisa mumagetsi emasero emasik ...

    1346546-69-7 GSK872 (1346546-69-7)

    GSK872 is aa receptor inobatanidza protein kinase-3 (RIP3) inhibitor. GSK872 inhibits TNF- uye utachiona hunokonzerwa necrosis mu 3T3-SA fibroblasts. ...

    443797-96-4 JNJ7706621 (443797-96-4)

    JNJ-7706621 pane pan-CDK inhibitor ine simba rakanyanya pane CDK1 / 2 ne IC50 ye9 nM / 4 nM nekuratidza> 6-fold selectivity yeCDK1 / 2 kupfuura ...

    1073485-20-7 LDC000067 (1073485-20-7)

    LDC000067 inonyanya kusarudza CDK9 inhibitor ne IC50 ye44 nM, 55 / 125 / 210 /> 227 /> 227-fold selectivity pane CDK2 / 1 / 4 / 6 / 7 ....

    1453834-21-3 LDC4297 (1453834-21-3)

    LDC4297 inobudisa CDK7 inhibitor (IC50 = XUMUMI ± 0.13 nM yeCDK0.06 neIx7 pakati pe50 nM uye 10 nM yezvimwe zvose zvakaongororwa CDK).

    ...

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