Nei Tichida Nicotinamide Riboside Chloride

Iyo cosmetic indasitiri yemabhiriyoni emadhora indasitiri, zvikuru nekuti vanhu vakasarudzika nemaitiro avo anotaridzika. Ichi ndichozve chinhu chakakosha nei tsvakiridzo ichitenderedza kupesana nekukwegura uye zvigadzirwa yakaita fambiro mberi inoshamisa zvakadaro munguva pfupi. Vemakomisheni epasi rose vanonzwisisa kuti kune mari inogadzirwa kubva mukuda kwevanhu kuti varambe vari vadiki nekusingaperi, nekudaro vane zvikwata munzvimbo, vanopedza mazuva nemavhiki kuti vawane zvinogadzirwa uye zvigadzirwa zvinokwanisa kuwedzera ganda simba. Nicotinamide Riboside kana Niagen yakawanikwa semugumisiro wekutsvaga uku kusingaperi kwezve anti-kukwegura zvigadzirwa. Nepo zvigadzirwa zvizhinji zvinopesana nekukwegura zvichideredza zviratidzo zvekukwegura kubva paganda, Niagen inoderedza zviratidzo zvekusakura mukati memuviri. Nicotinamide Riboside kana Niagen ndiyo fomu yekristaro ye Nicotinamide Riboside Chloride uye kamwe mukati memuviri, inoshandura kuita NAD +, iyo inotarisira kukwegura kune hutano pamwe nemamwe mabasa akakosha.

Mune ino chinyorwa, tinotaura zvese zvikamu zveichi chinoshamisa chinjo, kusanganisira zvayakanakira, mhedzisiro-yakakodzera uye yakakodzera dosage.

Chii chinonzi Nikotinamide Riboside Chloride?

Nicotinamide Riboside Chloride kana Niagen ndiyo kristaro fomu yaNikotinamide Riboside, inova NAD + precursor vhitamini. Ipo Nikotinamide Riboside inorema 255.25 g / mol, Nicotinamide Riboside Chloride inorema 290.70 g / mol uye 100 mg yaNicotinamide Riboside Chloride inopa 88 mg yeNicotinamide Riboside. NR inoonekwa yakachengeteka kushandiswa muzvikafu.

Kunyangwe Nicotinamide Riboside iri fomu yeVitamin B3, zvimiro zvakasiyana siyana zvinoita kuti zvisiyane kubva kune dzakawanda dzimwe nhengo dzeboka revhitamini B3, senge nicotinamide uye niacin. Nepo Niacin ichikonzera kuti ganda ridziye nekumedza iyo GPR109A G-protein yakabatana receptor, Nicotinamide Riboside haina kana zvachose neiyi receptor uye nokudaro, haina kana kukonzeresa kuganda kweganda, kunyangwe kana ichidyiwa yakakwira huwandu hwe2000 mg pazuva. Kupfuurirazve, kuedza kwakaitwa pamakonzo kwakaratidza kuti Nicotinamide Riboside ndiyo NAD + yekutanga iyo yakakonzera kune yakanyanya kukwirira muNicotinamide Adenine Dinucleotide kana NAD + mukati memuviri.

Nicotinamide Riboside inoitika nechero mukudya kwemunhu uye kamwe mukati memuviri, inochinja kuita NAD +, iyo inodiwa nemuviri mabasa akasiyana siyana. Semuenzaniso, kutsvagurudza kwesainzi kwakaratidza kuti Nicotinamide Riboside Chloride kana NAD + yakapihwa naNR inovandudza mitochondrial basa pamwe nekunzwa kwe insulin nekumisa mhuri yevahertuin ma enzymes, ayo ane basa rekugadzirisa oxidative metabolism mukati memuviri.

Parizvino, zvidzidzo zvishanu zvakaitwa kuti zvidzidze kuchengetedzwa uye kushanda kweNicotinamide Riboside uye zvese izvi zvidzidzo zvakawana kuti cheni yacho yakachengeteka kuti ishandiswe nevanhu.

Nicotinamide Riboside Chloride Benefits

Tisati takurukura nezve zvakanaka zveNicotinamide Riboside Chloride, zvakakosha kujekesa kuti sezvo Nikotinamide Riboside Chloride ari munyu unowanikwa maNicotinamide Riboside, mabhenefiti aNicotinamide Riboside Chloride akafanana nezvibatsiro zvaNicotinamide Riboside.

Nicotinamide Riboside Chloride Inosimudzira Hutano Kukwegura

Iyo NAD + yakagadziriswa naNicotinamide Riboside Chloride mukati memuviri inoshanda chaiyo ma enzymes anobatana nehutano hwekukwegura. Imwe enzyme yakadaro ishertuins, iyo yakabatana nehupenyu hwese hwakagadziridzwa uye hupenyu hwehupenyu mumhuka. Zvidzidzo zveSainzi zvakaratidza kuti masisittu anovandudza hupenyu hwehupenyu uye hupenyu hurefu nekudzikisira kuzvimba, kuwedzeredza mabhenefiti ane hukama ne calorie kurambidzwa uye kugadzirisa iyo yakakanganisika DNA. Iyo NAD + yakagadziriswa naNicotinamide Riboside Chloride zvakare inosimudzira Poly polymerases inozivikanwa kugadzirisa yakakanganisika DNA. Kupfuurirazve, zvidzidzo zvinoverengeka zvesainzi zvakabatanidza basa rema polymerases nehupenyu hwakawedzerwa hupenyu.

Iyo Inoderedza Mikana Yemumwe Yekukudziridza Hosha dzeMwoyo

Kuchembera kunowedzerawo mikana yemunhu yekurwara nemoyo. Sezvo vanhu vanoramba vachikura zera, tsinga dzeropa ravo dzinova diki uye dzakaomarara, uyezve, zvinounza kuwedzera kweropa. Kana dzvinyiriro yeropa mukati memidziyo ichiwedzera, moyo unofanirwa kushanda zvakapetwa kupomha ropa, zvinova zvinotungamira pazvirwere zvemwoyo zvakasiyana. Iyo NAD + yakapihwa naNicotinamide Riboside Chloride inodzosera shanduko-inoenderana nezera yakakonzerwa nemitsipa yeropa. Pane huchapupu hwakakwana hwesainzi hwekuratidza kuti Nikotinamide Adenine Dinucleotide kana NAD + haingoderedze kusimbisa kweropa chete asiwo inotungamira systolic yeropa.

Nicotinamide Riboside Chloride Inopawo Dziviriro kuBongo Masero

Nicotinamide Riboside inochengetedza masero europi. Kuongororwa kwakaitwa pamakonzo kwakaratidza kuti NR-yakasimudzira kugadzirwa kweNAD + yakawedzera kugadzirwa kwePGC-1 alpha protein nekukwira kusvika makumi mashanu muzana. Iyo PGC-50 alpha mapuroteni anobatsira kuchengetedza maseru epfungwa kubva kune oxidative kusagadzikana uye zvakare kunatsiridza mitochondrial basa. Ndoku, saka, kuti kunwa kweNR muvanhu kudzivirira kubva kuchirwere chakapinza cheuropi, akadai seAlzheimer's neParkinson's. Imwe ongororo yekutsvagiraka yakadzidza mabudiro ehuwandu hweNAD + pane vanhu vanotambura neParkinson's. Chidzidzo ichi chakagumisa kuti NAD + yakavandudza mitochondrial basa mumasisitimu eiri.

Zvimwe Zvikonzero Zvakakosha zveNicotinamide Riboside Chloride

Zvimwe kunze kwekubatsira kwakakurukurwa pamusoro apa, heano mamwe mashoma ekuwedzera mabhenefiti akabatana neNicotinamide Riboside Chloride.

  • NR inozivikanwa kukwidziridza simba remhasuru, kushanda uye kutsungirira uye saka, NR yekushandisa inosanganisirwa neiri nani mutambo wemitambo.
  • Sezvakakurukurwa pamusoro, NR-yakasimudzira kugadzirwa kweNAD + inogadzirisa DNA uye inopa kudzivirirwa kubva kune oxidative kusagadzikana. Izvi, zvakare, zvinodzora mikana yemunhu yekukonzera kenza.
  • Chidzidzo chakaongorora mhedzisiro yaNicotinamide Riboside pane metabolism mumakonzo. Chidzidzo chacho chakagumisa kuti NR yakawedzera metabolism mumakonzo. Kunyangwe kuchinyanya kuwanikwa hunyanzvi chesainzi maererano neizvi, masayendisiti mazhinji anotenda kuti Nicotinamide Riboside ichave nemhedzisiro yakafanana pane vanhu uye nekudaro, inofanira kubatsira nekudzikisira uremu.

Nicotinamide Riboside Chloride

Nicotinamide Riboside Chloride Dosage

Izvo zvidzidzo zvishanu zvakaitwa kusvikira zvino zvakaratidza kuti Nicotinamide Riboside yakachengeteka kushandiswa kwevanhu. Nekudaro, izvi zvidzidzo zvakaratidza zvakachengeteka Nicotinamide Riboside Chloride muyero muganho wevanhu pasi pegumi kusvika zviuru zviviri mg pazuva. Nekudaro, inofanira kuchengetwa mundangariro kuti dzese idzo ongororo dzakaongorora kuchengetedzeka kwaNicotinamide Riboside yaive nechero diki remuenzaniso uye nekudaro, kutsvakisisa kwakawanda kunodiwa munzvimbo ino.

Chinangwa chekutanga cheNicotinamide Riboside Chloride ndeyekupa chaizvo Nicotinamide Riboside Chloride kana Niagen kumuviri. Niagen kana NR inowanzo kuwanikwa mune maviri mafomu: mahwendefa uye makapu. Vazhinji Nicotinamide Riboside supplement vagadziri vanobatanidza NR nemamwe makemikari, akadai saPterostilbene. Chero zvazvingaitika, kuti uve akachengeteka, vagadziri vazhinji vanowedzera vanokurudzira kuchengetedza kudya kwemazuva ese kweNR pakati pe250 kusvika 300 mg pazuva.

Is Nicotinamide Riboside Chloride Yakachengeteka?

Izvo zvidzidzo zvinoverengeka zvakaitwa kusvika parizvino zvakawana Nicotinamide Riboside yekushandisa mune ye1000 kusvika 2000 mg pazuva pazuva yakachengeteka kushandiswa kwevanhu. Nekudaro, sezvo zvakanyanya kongiri kudzidza kuchidikanwa munzvimbo ino, Vagadziri veNicotinamide Riboside vanokurudzira kuchengetedza munhu zuva nezuva yekudya kweNR pasi pe250 300-XNUMX mg pazuva.

Kunyangwe Nicotinamide Riboside kana Nicotinamide Riboside Chloride yekushandisa yakachengeteka, inogona kutungamira nekukonzera mhedzisiro dzakadai sekushungurudzika, kutemwa nemusoro, kudzimbira, kupera simba uye manyoka. Kana mukawana chimwe zvezviratidzo izvi apo watora NR chinamatidzwa, pakarepo bvunza chiremba wako. Uyezve, sezvo pasina humbowo hwakakwana maererano nehunhu hwaNikotinamide Riboside pamadzimai ane pamuviri uye anoyamwisa, boka iri rinofanira kurega kushandiswa kweNicotinamide Riboside supplements.

Nicotinamide Riboside Chloride chinamatidzwa

Kana iwe uchitsvaga miriwo Nicotinamide Riboside Chloride kuwedzera, tinokurudzira Tru Niagen Nicotinamide Riboside supplement. Ichi chiwedzerwa chinoshandisa NIAGEN, iyo kambani ine patent yeNR chigadzirwa. Iyo kambani yekugadzira inoshanda chete neNicotinamide Riboside supplements uye nekudaro, munhu anogona kuzorora kuti zvinowedzera zvinogadzirwa nekambani ndeemhando yepamusoro kwazvo. Iyo Tru Niagen Nicotinamide Riboside yekuwedzera inouya mune-nyore-kushandisa-macapu emakapu, ayo ari nyore-nyore kumedza. Vashandisi vanofanirwa kutora chete imwe capsule pazuva.

Nekudaro, kana iwe uchitsvaga gluten, zai, BPA, nzungu, mishonga yekuchengetedza uye isina-chigadzirwa, tinokurudzira kuisa mari yako muTorne ResveraCel Nicotinamide Riboside supplement. Ichi chinowedzera chinosanganisa NR ne flavonoids. Pamwe chete, izvi zviviri zvinowedzera Sirtuin chiitiko. Zvinotonyanya kukosha, Thorne ResveraCel inotaura kuti inoita makiromita mana ekuyedza pane imwe neimwe yekuwedzera uye nekudaro, zvinowedzera zvemakambani zvakachengeteka zvakakwana. Kupfuurirazve, izvi zvinongedzwa zvinogadzirwa mune cGMP yakasimbiswa nzvimbo muUnited States uye TGA yakasimbiswa nzvimbo muAustralia.

Nicotinamide Riboside Chloride

Kwokutenga Nicotinamide Riboside Chloride Powder muBhurandi?

Kudiwa kweNicotinamide Riboside supplements kwakawedzera zvakanyanya mumakore mashoma apfuura, kunyanya nekuda kwekuti Nikotinamide Riboside ine zvakawanda zvakanaka. Kana iwe uri kutsvaga kuzotungamira mumusika weNicotinamide Riboside supplements musika, chinhu chekutanga chaunofanira kuita kuzviwana iwe wakavimbika uye akavimbika zvigadzirwa zvekutengesa zvinhu. Kupi tenga Nicotinamide Riboside Chloride poda yakawanda? Mhinduro ndeyo Cofttek.

Cofttek ndeyezvigadzirwa zvekutengesa zvinhu zvakavapo muna2008 uye munenge makore gumi chete, kambani yakatanga kuvapo munyika dzakati. Kunze kwekugadzira zvigadzirwa zvakavimbika, kambani inoiswawo mukufambira mberi mumunda webiotechnology, tekinoroji yemakemikari uye kuyedzwa kwemakemikari. Iyo kambani yakazvipira zvakare pakutsvagiridza zvemhando yepamusoro, iyo inoipa iyo yakadzika pamusoro pevamwe vatengesi mumusika. The Nicotinamide Riboside Chloride powder inopiwa nekambani inouya mumabheti makumi maviri nemashanu emakirogiramu uye inogona kuvimbwa nemhando yepamusoro. Zvakare, iyo kambani ine yakanakisa kutengesa uye vatengi rutsigiro timu iyo inotarisira zvese zvaunoda uye kubvunza mune chaiyo-nguva. Izvi, kana iwe uchida kutenga Nicotinamide Riboside Chloride powder yakawanda, vimba neCofttek chete.

References
  1. Conze, D., Brenner, C.. Sci Rep9, 9772 (2019)
  2. Carlijn ME Remie, Kay HM Roumans, Michiel PB Moonen, Niels J Connell, Bas Haskes, Julian Mevenkamp, ​​Lucas Lindeboom, Vera HW de Wit, Tineke van de Weijer, Suzanne ABM Aarts, Esther Lutgens, Bauke V Schomaker, Hyung L Elfrink, Rubén Zapata-Pérez, Riekelt H Houtkooper, Johan Auwerx, Joris Hoeks, Vera B Schrauwen-Hinderling, Esiteri Phielix, Patrick Schrauwen, Nicotinamide riboside supplementation alters body composition and skeletal misuli acetylcarnitine concentrations mune vane hutano hwakanaka vanhu. The American Journal of Clinical Nutrition, Vhoriyamu 112, Chinyorwa 2, Nyamavhuvhu 2020, Mapeji 413–426
  3. Elhassan, YS, Kluckova, K., Fletcher, RS, Schmidt, MS, Garten, A., Doig, CL, Cartwright, DM, Oakey, L., Burley, CV, Jenkinson, N., Wilson, M., Lucas , S., Akerman, Ini, Seabright, A., Lai, YC, Tennant, DA, Nightingale, P., Wallis, GA, Manolopoulos, KN, Brenner, C.,… Lavery, GG (2019). Nicotinamide Riboside Augions iyo Akwegura Yevanhu Skeletal Muscle NAD + Metabolome uye Induces Transcripttomic uye Anti-immune Signature. Cell inoshuma, 28(7), 1717-1728.e6.
  4. Nicotinamide Riboside Chloride powder

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