Chii OLEOYLETHANOLAMIDE (OEA)?

Oleoylethanolamide inoumbwa nemazwi matatu: oleoyl, ethanol, uye amide. Kuti zvive nyore kwatiri, tinozvinongedzera ku OEA muchidimbu. Iyo inozivikanwawo se oleothanolamine.

Iyo yakasarudzika ethanolamide lipid inoshanda semutongi zvine chekuita nezve nzira yekudyisa uye huremu hwemuviri mune ese marudzi emhuka. Iyo metabolite ye oleic acid iyo inogadzirwa mudumbu diki remuviri wemunhu. Iyo yakasungirirwa kune PPAR Alpha receptor iyo inobatsira kudzora zvinhu zvina: nzara, mafuta emuviri, cholesterol, uye huremu. PPAR Alpha zvinoreva Peroxism Proliferator-Yakagadziriswa Receptor Alpha.

KUSHANDA KWEMAOLELELETHANOLAMIDE (OEA)

OEA kana Oleoylethanolamide mushonga unobatsira iwe kudzora uremu, tsika dzekudya, uye cholesterol. Iyo yakasikwa metabolite. Inogadzirisa mafuta emuviri wako nekuwedzera metabolism yemafuta aripo mumuviri wako. Inoshanda nenzira inonakidza kwazvo.

Sezvo uye paunotora chikafu, uyu mushonga unozotumira chiratidzo kuuropi hwako uchikumbira kuti urege kudya kana kutora chero chimwe chikafu sezvo muviri wako watotora chikafu chakaringana uye usingachade. Nekudaro, iwe unotanga kunzwa kuti waguta uye nekudaro unomira kudya. Nekudaro, zvishoma nezvishoma iwe unoramba uchitora huwandu huwandu hwechikafu nguva imwe neimwe nguva dzose. Nekudaro, mukufamba kwenguva, iwe unogona kugona kudzikisa huremu kusvika padanho rakakura.

Rumbidza

Iwo anoshanda mhedzisiro yeOEA uye ayo anobatsira zvinhu zvakawanikwa makore makumi mashanu apfuura. Pakanga pasina kutsvagiswa kwakanyatsorongeka nezve OEA gore risati rasvika 2001. Ndivo vaongorori vekuSpain vakatanga kudzidza nezve OEA, vakaedzwa pamakonzo kuti vaone mhedzisiro. Chidzidzo ichi chakataura kuti OEA haina mhedzisiro pahuropi asi inogona kuchinja maitiro ekudya uye ine chekuita nehunza hunhu.

Iko molecular formula ndeye C2OH39NO2. Iyo yakasarudzika CAS nhamba iri 111-58-0. OEA mubatanidzwa we oleic acid uye ethanolamine. Mukuvapo kwemafuta akapfuma aripo pachikamu chepamusoro chemuura mudiki mumuviri wedu ndipo panonyanya kuitirwa synthesis yezvinhu zviviri izvi. OEA yakafanana chaizvo uye yakafanana kune endocannabinoid anandamide asi zvirinani zvirinani.

ZVINOBATSIRA OLEOYLETHANOLAMIDE (OEA)

OEA ichokwadi chinodhaka chinowanikwa mumusika. Zvinotevera ndezvimwe zvinonyanya kukosha mabhenefiti eOEA.

1.UNODEREDZA CHIDZIDZO cheGHRELIN

Ghrelin ihormoni inowanika mumuviri wedu inokurudzira kuda kwedu. Izvo zvakawanikwa kuti OEA inobatsira kudzikisa huwandu uhwu hwehomoni mumuviri wedu kana iyi OEA ichipihwa.

2. ANODZORESA MUFODI MAFUTA PAKUWEDZERA KUNYANYA

Iyi jekiseni inowanikwa ichinyatsoita mukuderedza mafuta emuviri uye naizvozvowo pamutengo unowedzera. Inowedzera iyo metabolism mhedzisiro yemitochondria. Iyo inotoderedza kunwa kwechikafu nenzira inoshanda uye inowedzerawo simba remuviri wako.

OLEOYLETHANOLAMIDE

3.KEEPS PEPTIDE YY ZVIZVI

Peptide YY ihormone inosimudzira kuda kwedu. OEA majekiseni kana akatorwa anobatsira kudzikisira uye nekuchengetedza huwandu hwePeptide YY mahormone mwero yakaderera.

4.IYO INOBATSIRA KUTONGA CHIDA

Kutora OEA jekiseni kunobatsira kudzora chishuwo nekupfupisa nzvimbo yemafuta mumuviri wedu. Inotowedzera kupisa kwemafuta akaunganidzwa mumitumbi yedu. Sezvo uye paunotora chikafu, OEA inotanga kushanda. Inosimudza mashandiro ayo uye panguva imwe chete inoderedza huremu hwako hwekuda nekutumira mamaki kuuropi uye inozivisa kuti wagutsikana zvakanyanya uye haudi chimwe chikafu chekudya.

5.NO SIDE ZVINOGONESESA

Mushure mekuongorora iyo OEA, zvakafungidzirwa kuti hapana munhu akatarisana nemimwe mhedzisiro yakaipa mushure mekuiisa mumuviri. OEA i oleic acid inotorwa sechikamu chekudya kwako kune hutano uye kunovaka muviri.

6.ZVINOGONESESA PAKUShushikana

OEA inokanganisa kushushikana. Iko kudya kweOEA kunobatsira kuchengetedza pfungwa dzako kusununguka kubva mukuzvidya mwoyo uye nekudaro kunobatsira mukuchengetedza zvirwere zvekushushikana.

7.Inowedzera HDL Mumuviri

Kune marudzi maviri echolesterol aripo mumuviri wedu. Ivo- LDL Cholesterol uye HDL Cholesterol. LDL ndiyo cholesterol yakaipa uye HDL ndiyo cholesterol yakanaka. Kudya kweOEA kunobatsira kudzikisa LDL Cholesterol uye kuwedzera HDL Cholesterol.

8.AIDS MUKUVAKA MUVIRI

Kuvaka muviri wako muchimiro chakarongeka uye muchimiro uye zvakaenzana ndeimwe yemafashoni azvino munyika yanhasi. Kunyanya mufashoni kana indasitiri yevaraidzo mune chimiro muviri inodiwa kwazvo. Kudya kwe OEA kunobatsirawo mukuvaka muviri sezvo uchidzikisa mafuta mumuviri wako.

OLEOYLETHANOLAMIDE

Chiyero che OLEOYLETHANOLAMIDE (OEA)

Chiyero cheOEA inogona kutorwa nenzira mbiri zvichienderana nezano rachiremba:

1.OEA yakatora pasina chero imwe yekudzikisa uremu yekuwedzera

Kana iyo OEA capsule ikatorwa pasina chero huremu hwekudzikisa huwedzero saka unogona kutora 1 OEA capsule ye200mg.

2.OEA yakatora neimwezve yekudzikisa uremu yekuwedzera

Kana iyo OEA capsule ikatorwa pamwe chete nehumwe huremu hwekudzikisa huremu saka unogona kutora 1 OEA capsule ye100 mg kusvika 150 mg.

Mumwe anofanirwa kutora OEA capsule maminetsi makumi matatu asati adya. Izvi zvinokuchengetedza kuti ugutsikane iwe paunenge uchidya uye nekudaro unozopedzisira uchidya hushoma huwandu hwechikafu.

Uyezve, iwe unogona kutowedzera kana kudzikisa iwo mwero wezuva rako muyero weOEA kunoenderana nehuremu hwemuviri wako. Ngatitii, munhu ari kuyera 150 lb anotora muOEA capsule ye100mg. Asi kana munhu achirema 250 lb, anogona kutora OEA capsule ye180 mg.

KUSHANDISWA KWA OLEOYLETHANOLAMIDE (OEA)

Zvishandiso zveOEA zvinoshanda nenzira ine hungwaru. Kutanga, inowedzera mukaha panguva pakati pekudya kumwe kunotevera kudya. Kechipiri, zvinobatsira mukuderedza kushanduka kwe circadian. Chechitatu, inochengetedzwa nemishonga inowanikwa.

OLEOYLETHANOLAMIDE

ZVINOGONESESWA ZVEMAZUVA OLEOYLETHANOLAMIDE (OEA)

OEA ine oleic acid. Nekudaro, izvo zvikafu zvine oleic acid zvakanangana uye sosi sosi yeOEA. Miriwo yemafuta semafuta emuorivhi, mafuta eCanola, mafuta ezuva (sunflower) ane oleic acid ndiyo yakasikwa zvinowedzera zveOEA. Iwe unogona kutowana oleic acid muhuku, chizi, nyama, uye maoiri emafuta zvakare zvinowedzerwa zveOEA. Iwe unogona kunyange kutora oleic acid mumukaka wemukaka uye saka vacheche vacheche vanofanirwa kuyamwiwa kwenguva yakareba sezvinobvira.

Asi dambudziko nderekuti chiyero chekuburitsa OEA kubva kuchikafu chechisikigo chakanyanya kwazvo. Kupfuura paavhareji inoyera 15: 1, iyo isina kukwana zvakakwana kuzadzikisa kudiwa kwevatengi vepasirese. Kubviswa kweiyo OEA mwero kunogona kuwedzerwa zvisinei nemari yekuita izvi ichave yakakwira zvekuti zvese zvinoguma zvisina maturo. Nekudaro, zvingangoita padhuze nekusagoneka kuburitsa OEA yakawanda kubva kuchisikigo nzira

Saka, chekutanga OEA inobviswa mu oleic acid. Ipapo inoshandiswa kuve mutungamiriri weN-oleoylphosphatidylethanolamine. Nhanho inotevera inosanganisira kuipatsanura neN- acylphosphatidylethanolamine -kuita phospholipase D (PLD) kununura OLEOYLETHANOLAMIDE (OEA).

MUDZIMAI WOKUDZIDZA WACHO OLEOYLETHANOLAMIDE (OEA)

Mumwe anogona kutenga mushonga weOEA kubva kune inozivikanwa uye ine hunyanzvi chitoro chemishonga chiri padyo nepako pekugara kana kutogona kuitenga nekuodha online. Asi mumwe anofanirwa kuve akangwarira mune izvi sezvo vese vanopa mushonga uyu vangasave vechokwadi.

Saka, gara uchitarisa mukurumbira uye kugona kweiyo online online zvitoro uye nekuda kweizvozvo, zvinogara zvichikurudzirwa kuti uende kuburikidza nehukama hweongororo dzevatengi vane ruzivo. Ive neshuwa nezve kurongedzwa kwechigadzirwa senge chakavharwa mushe kana kuti usadzivise chero rudzi rwekusvibisa izvo zvinogona kukonzeresa kune dzimwe nyaya dzine njodzi pamberi pehutano.

OLEOYLETHANOLAMIDE (OEA) MUFOMU YEPODHA

OEA mune yayo yekutanga mamiriro haina kuwanikwa muchimiro chemapiritsi kana macapsule. Zvisinei, unogona tenga OEA upfu muhuwandu mumusika kana zvichidikanwa. Iyi fomu yehupfu inosanganisirwa mune zvakapedzwa chigadzirwa nekuzvigadzirisa kusvika pa15% OEA kana 50% OEA oleic acid. Chirongwa cheCima OEA chinochengetwa pakati pe90% kusvika 95% kunyanya pakati pevatengi veEurope neUnited States.

tenga OLEOYLETHANOLAMIDE (OEA) upfu MUBHUKU

Iwe unogona kuisa odha repamhepo yekutengwa kwakawanda kwehupfu kana unogona kunyange kutenga kubva kune kunozivikanwa zvitoro zvemuno. Kuchengetedza kwakanaka zvakapusa mune iyo OEA upfu. Iwe unofanirwa kuzvichengeta pane tembiricha yemukati. Asi, haifanire kusangana nehunyoro kana yakananga zuva mwaranzi. Nekudaro, iwe unofanirwa kuichengeta yakasimba yakavharwa munzvimbo inotonhorera uye yakaoma.

STABILITY

Zvishandiso zveOEA inogona kukubatsira munzira dzakawanda! Neichi chikonzero, inokurudzirwa kune wese munhu sezvo isina mhedzisiro. Inogona kutokonzeresa mararamiro ane hutano mukati memhuri yako ichiita kuti mese mukure uye mupenye muchimiro, maitiro, uye nekuremekedza uye kuvimba. Kuchengeta nekuchengetedza muviri wako uri muchimiro, kunyanya kune avo vakafuta zvishoma, hakuzoite chete kuti unzwe uchifara asi kuchaitawo kuti vamwe vanzwe kufara uye kudada newe.

OEA zvakare ichakubatsira iwe kuburitsa kushushikana kwepfungwa ichikubatsira iwe kuti uve nemuratidziro wakanaka mupfungwa dzevamwe. Nekudaro, pachinzvimbo chekunzwa kugumbuka uye kusafara, inguva yakakwira yekuita chiito uye wotanga kushandisa OEA uye iwe unozoshamiswa zvakanyanya kuona masimba ayo emashiripiti uye iwe unonzwa kupora uye kubatwa.

References:
  1. Pi-Sunyer FX, Aronne LJ, Heshmati HM, Devin J, Rosenstock J. Mhedzisiro ye rimonabant, iyo cannabinoid-1 receptor blocker, pane uremu uye cardiometabolic njodzi zvinhu muvarwere vakanyanya kana vakafuta: RIO-North America: muyedzo wakatemwa wakatemerwa. Iyo Journal yeAmerican Medical Association. 2006; 295 (7): 761-775.
  2. Giuseppe Astarita; Bryan C. Rourke; Johnnie B. Andersen; Jin Fu; Janet H. Kim; Albert F. Bennett; James W. Hicks & Daniele Piomelli (2005-12-22). "Postprandial kuwedzera kwe oleoylethanolamine kuunganidza mune dumbu ura hweBurmese python (Python molurus)". Ndiri J Physiol Regul Yakabatana Yakabatana Physiol. 290 (5): R1407 – R1412.
  3. Sarro-Ramirez A, Sanchez-Lopez D, Tejeda-Padron A, Frias C, Zaldivar-Rae J, Murillo-Rodriguez E. Brain mamorekuru uye kusadya: nyaya ye oleoylethanolamide. Central Nervous System Agents muMedical Chemistry. 2013; 13 (1): 88-91.

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