Coluracetam (135463-81-9)

Dai 8, 2021

Raw Coluracetam powder inoratidzika kuwirirana nehutano hunozivikanwa sehukama hwepamusoro hwecholine hutsva (HACU kwenguva pfupi), iyo ndiyo danho rekugadzirisa-kukonzera kukonzera choline mu neuron kuti iende neurotransmitter acetylcholine. Kuwedzerwa kwehuwandu hweHACU kunoonekwa kuwedzera basa re cholinergic neurons, saka icho chinoda chinangwa chekugadzirisa pfungwa.

Coluracetam (135463-81-9) Specifications

Name: Coluracetam
CAS: 135463-81-9
Purity 98%
Molecular Formula: C19H23N3O3
Molecular Kurema: 341.411 g / moll
Melt Point: N / A
Kemikari zita: N-(2,3-dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide

MKC-231

bci-540

Synonyms: Coluracetam; BCI-540; MKC-231; BCI 540; MKC 231; BCI540; MKC231.
InChI Key: PSPGQHXMUKWNDI-UHFFFAOYSA-N
Hafu Hupenyu: N / A
Solubility: Yakasanganiswa muDMSO
Chengetedzo Chimiro: Kuoma, kusviba uye pa0 - 4 C kwenguva pfupi (mazuva kusvika kumavhiki) kana -20 C kwenguva refu (mwedzi kusvika makore)
Application: Raw Coluracetam powder (MKC-231) inogadzira racetam zvinodhaka zvinonzi inonzi nootropic.
Kuonekwa: white white crystalline powder

 

Coluracetam (135463-81-9) NMR Spectrum

Coluracetam (135463-81-9) NMR Spectrum

Kana iwe uchida COA, MSDS, HNMR kune rimwe nerimwe batch yechigadzirwa uye rumwe ruzivo, ndapota nyorera vedu mutengesi wekushambadzira.

 

Chii Coluracetam (135463-81-9)?

Raw Coluracetam powder (MKC-231) inogadzira racetam zvinodhaka zvinonzi inonzi nootropic. Haina hukuru hwehupupuri hunotsvakurudza, asi nzira dzekuita (pamwewo nekugadzirisa) dzinoita se dzakasiyana zvikuru nedzimwe marcetam mazana akaita sePiracetam kana Aniracetam.

Raw Coluracetam powder inoratidzika kuwirirana nehutano hunozivikanwa sehukama hwepamusoro hwecholine hutsva (HACU kwenguva pfupi), iyo ndiyo danho rekugadzirisa-kukonzera kukonzera choline mu neuron kuti iende neurotransmitter acetylcholine. Kuwedzerwa kwehuwandu hweHACU kunoonekwa kuwedzera basa re cholinergic neurons, saka icho chinoda chinangwa chekugadzirisa pfungwa.

 

Coluracetam (135463-81-9) zvinobatsira

  • Kuvandudza Memory uye Kudzidza
  • Kuvandudza Kuverenga Kunzwisisa uye Mahara Yeuka
  • Yakareba Kugadziriswa Kwekunzwisisa Kunatsiridza
  • Deredza Kurapa-Kuramba Kushungurudzika
  • Inogona kukurudzirwa Neurogeneis
  • Inogona kuvandudza Kurwara Kwepfungwa
  • Dai Kuvandudza Chiratidzo
  • Irritable Bowel Syndrome chiratidzo kugadzirisa
  • Coluracetam yekuvaraidza kushandiswa

 

Coluracetam (135463-81-9) tizvishandise

Coluracetam (INN) (kodhi zita BCI-540; yaimbove MKC-231) poda inhengo ye nootropic yemhuri ye racetam. Yakatanga kugadzirwa uye kuyedzwa neMitsubishi Tanabe Pharma Corporation yechirwere cheAlzheimer. Mushure mekunge mushonga uyu wakundikana kusvika kumagumo mumiedzo yawo yemakiriniki wakapihwa-rezinesi neBrainCells Inc yekuferefeta dambudziko rakakura rekuora mwoyo (MDD), iro rakatungamirwa nekupihwa "Inokodzera Therapiki Discovery Chirongwa Grant" nenyika yeCalifornia.

 

Coluracetam (135463-81-9) Dosage

Zvizhinji zvekutsvakurudza pamusoro pekoruracetam zvakaitwa pamhuka panzvimbo pevanhu, saka hapana mazano anogamuchirwa munyika yose. Iko inoshandiswa dheji yakatarisa inowanzotsanangurwa se 5-20 mg. Vashandi veColuracetam vakarondedzera maitiro akawanda akasiyana-siyana anotungamirirwa nomuromo uye zvinyorwa.

Mhinduro yemushandisi yakataura zvakare kuti kushivirira kune coluracetam powder kunogona kukurumidza kukurumidza. Sezvakaita nemishonga yese, kunyanya nootropics, zviri nani kutanga pamadosi madiki uye kukwirisa dosi zvishoma nezvishoma sezvo muviri wako unoita uye uchigadzirisa kumushonga. Coluracetam haina chepfu uye inoonekwa seyakashongedzwa zvakanaka uye yakachengeteka.

 

Coluracetam powder Sale(Iko Kwekutenga Coluracetam powder muhuwandu)

Kambani yedu inonakidzwa nehurefu hwehukama nevatengi vedu nekuti tinotarisa pakubata kwevatengi nekupa zvigadzirwa zvikuru. Kana iwe unofarira chigadzirwa chedu, isu tinoshanduka pamwe neyakagadziriswa yemirairo kuti ikwane yako chaiyo yekuda uye yedu yekukurumidza kutungamira nguva pamirairo inovimbisa kuti uchave nekuravira kwedu kukuru chigadzirwa pane-nguva. Isu tinotarisawo pamabasa akawedzerwa-kukosha. Isu tinowanikwa yemibvunzo yebasa uye ruzivo rwekutsigira rako bhizinesi.

Isu tiri nyanzvi yeColuracetam yeupfu mutengesi kwemakore akati wandei, isu tinopa zvigadzirwa nemakwikwi mutengo, uye chigadzirwa chedu chiri chemhando yepamusoro uye chinoitwa nekuomarara, kwakazvimirira kuyedzwa kuona kuti yakachengeteka kudyiwa pasirese.

 

References

[1] Akaike A, et al. (1998). Inodzivirira mhedzisiro yeMKC-231, inoverengeka yakakwenenzverwa choline inotora inosimudzira, pane glutamate cytotoxicity mune yakagadziriswa cortical neurons. Jpn J Pharmacol.

[2] Bessho, T., Takashina, K., Tabata, R., Ohshima, C., Chaki, H., Yamabe, H., Egawa, M., Tobe, A., & Saito, K. (1996). Mhedzisiro yenoverengeka yepamusoro yekudyidzana choline inotora inosimudzira 2- (2-oxopyrrolidin-1-yl) -N- (2,3-dimethyl-5,6,7,8-tetrahydrofuro [2,3-b] quinolin-4- yl) acetoamide pakushomeka kwemvura maze kudzidza mumakonzo. Arzneimittel-Forschung, 46 (4), 369–373.

[3] Murai, S., Saito, H., Abe, E., Masuda, Y., Odashima, J., & Itoh, T. (1994). MKC-231, choline inotora inosimudzira, inosimudzira kushomeka kwekurangarira uye kudzikira hippocampal acetylcholine inokonzerwa neethylcholine aziridinium ion mumakonzo. Zvinyorwa zveNeural Transmission, 98 (1), 1–13 / bf10.1007.

[4] Takashina K, Bessho T, Mori R, Eguchi J, Saito K. MKC-231, choline inosimudzira: (2) Mhedzisiro yekuumbwa uye kubudiswa kweacetylcholine muAF64A-kurapwa makonzo. J Neural Transm (Vienna). 2008 Jul; 115 (7): 1027-35. doi: 10.1007 / s00702-008-0048-1. PubMed PMID: 18446264.

[5] Shirayama Y, Yamamoto A, Nishimura T, Katayama S, Kawahara R. Achizotevera kuratidzwa kweiyo choline inosimudzira inowedzera MKC-231 inokanganisa phencyclidine-inosimudzira maitiro ekushomeka uye kuderedzwa kweiyo septal cholinergic neurons mumakonzo. Euro Neuropsychopharmacol. 2007 Sep; 17 (9): 616-26. PubMed PMID: 17467960.