Alfa-GPC (28319-77-9) Mugadziri wevanowanika fekitori

Alpha-GPC (28319-77-9)

April 7, 2020

Alfa GPC (alpha glycerophosphocholine), senge citicoline, inogona zvakare kubatsira neuroprotective basa. Iyo yakakomberedzwa yakaumbwa ne glycerophosphate uye choline.


Mamiriro: MuMitambo Yokugadzira
Unit: 25kg / Drum

Alpha GPC (28319-77-9) vhidhiyo

Alpha GPC Specifications

Name: Alpha GPC
CAS: 28319-77-9
Purity 50% isiri- hygroscopic poda ; 50% & 99% poda ; 85% yemvura
Molecular Formula: C8H20NO6P
Molecular Weight: 257.223 g / mol
Melt Point: 142.5-143 ° C
Kemikari zita: Alpha GPC; Choline Alfoscerate; Alpha Glycerylphosphorylcholine
Synonyms: (R) -2,3-dihydroxypropyl (2- (trimethylammonio) ethyl) phosphate; sn-Glycero-3-phosphocholine
InChI Key: SUHOQUVVLLYYQR-MRVPVSSYSA-N
Hafu Hupenyu: 4-6 maawa
Solubility: Soluble muDMSO, Methanol, Mvura
Chengetedzo Chimiro: 0 - 4 C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 C kwenguva refu (mwedzi)
Application: Alfa GPC (Choline Alfoscerate) is phospholipid; gwara rekutanga mune choline biosynthesis uye yepakati mune catabolic nzira ye phosphatidylcholine. Alpha GPC inoshandiswa seNootropic.
Kuonekwa: White powder

Chii chinonzi Alfa GPC (28319-77-9)?

Alfa GPC (alpha glycerophosphocholine), senge citicoline, inogona zvakare kubatsira neuroprotective basa. Iyo yakakomberedzwa yakaumbwa ne glycerophosphate uye choline. Alfa GPC ndeye yakasikwa yeyunivhesiti iyo inogonawo kushanda zvakanaka pamwe nemamwe ma nootropics. Alpha GPC inoshanda nekukurumidza uye inobatsira kuendesa choline kuuropi uye inonyatso kuwedzera kugadzirwa kweacetylcholine pamwe nesero membrane phospholipids. Izvo zvinogoneka iyo yakawandisa inogona zvakare kuwedzera kubudiswa kwe dopamine uye calcium.

Alpha GPC (28319-77-9) zvakanaka

Alpha GPC inounza pamwe nehuwandu hwekubatsira, imwe yezvakakosha kuve mukana wekuvandudza hutano hwehuropi uye kuziva. Izvo zvingave zvichikwanisika neAlf GPC yekuvandudza kugadzirwa kwemirangariro uye kuwedzera kugona kwekudzidza. Iyo inowoneka yekuvandudza ndangariro inobatsira kubva kune alpha GPC inogona kunyatso kudzorera ndangariro, asi mune mamwe mamiriro chete. Alpha GPC inokwanisawo kukwidza dopamine mazinga, ayo anobatsira uropi kushanda zvakanyanya.

Alfa GPC ndeye mvura inosungunuka phospholipid metabolite inoshanda seamberi yeacetylcholine (ACh) uye phosphatidylcholine (PC) biosynthesis mumuviri wese. Nekuda kweiyo chiitiko chechiitiko uye kugona kuyambuka kweropa-brain barriers, inoita kunge inonyanya kushanda cholinergic compound, kana ichienzaniswa choline neCDP-choline, uye inoshivirirwa chaizvo. Tsvagudzo inoratidza kuti alpha-GPC inotsigira mabasa mazhinji mukati meCNS inosanganisira: yekupindura kwekukurudzira, inotsigira kudzidza uye ndangariro, uye inogona kutora chinhanho mune hutano hwakanaka. Nekuda kwekupihwa kweglycerophosphate, alpha-GPC inoratidzikawo kutsigira chimiro uye basa rezvinhu zvemashupu e cell uye membrane yemaselula, uye inogona kutora chikamu mukutsigira hutano hwehuropi basa mukati mekukuvara kwekudzorera.

Alpha GPC (28319-77-9) Mechanism Yekuita?

Alfa GPC inosimudzira iyo cholinergic system iyo inotarisira zvinhu zvekuziva sekurangarira uye kufunga. Iyo yakasarudzika sosi ye choline inoshanda seamberi kune iyo neurotransmitter acetylcholine.

Acetylcholine inowanikwa zvakanyanya muuropi nemuviri uye inobatsira kune akawanda emakemikari mameseji atinotumira uye kugamuchira. Uye isvery inozivikanwa chaizvo nekudzidza pamwe nekuita mhasuru kusagadzikana nekudaro ichigadzira iyo hukama hwepfungwa. Alpha GPC inoshanda nekukurumidza uye inobatsira kuendesa choline kuuropi uye inonyatso kuwedzera kugadzirwa kweacetylcholine. Nekupa uropi hwako hwakawanda choline inogona kushandura iyo kuva acetylcholine uye kubatsira kune yakawanda yakadzika mhedzisiro. Kunyanya, acetylcholine inoshandiswa neiyo hippocampus kugadzira ndangariro.

Acetylcholine inoshanda nenzira dzakasiyana siyana dzekutsigira kwako kushanda kwekuita. Izvo zvinogona zvakare kuvandudza hunyanzvi hwako hwemitauro, kugona kwako kufunga uye kushandisa pfungwa, pamwe nehunyanzvi hwako. Izvi zvakafanana zvakakoshawo kurangarira, kurudziro, uye kufamba. Mazinga eiyo neurotransmitter zvakasikwa akavezera nezera. Kuve nechokwadi chekuti iwe une zvakakwana zveuropi izvi zvemakemikari zviripo kuti zviitike zvinodiwa nebasa rako rekuziva, unofanirwa kuramba uchikwidza.

Alpha GPC (28319-77-9) Kushandiswa

Alfa-GPC ndeyemakemikari inoburitswa kana mafuta anowanikwa mune soy uye zvimwe zvinomera zvikaputsa. Iyo inoshandiswa semushonga.

MuEurope alpha-GPC mushonga unorapa wekurapa chirwere cheAlzheimer. Inowanikwa mune maviri mafomu; imwe inotorwa nemuromo, uye imwe inopiwa sekupfurwa. MuUnited States alpha-GPC iri onlyava kuwanikwa sechikafu chinowedzera, kunyanya mune zvigadzirwa zvinokurudzirwa kugadzirisa ndangariro.

Zvimwe zvinoshandiswa kushandisa alpha-GPC zvinosanganisira kurapwa kwemhando dzakasiyana-siyana dze dementia, stroke, uye "mini-stroke" (inononoka ischemic attack, TIA). Alfa-GPC inoshandiswa zvakare mukuvandudza ndangariro, kugona kufunga, uye kudzidza.

Alpha GPC powder Sale(Ndekupi Kutenga Alfa GPC poda muhuwandu)

Kambani yedu inonakidzwa nehurefu hwehukama nevatengi vedu nekuti tinotarisa pakubata kwevatengi nekupa zvigadzirwa zvikuru. Kana iwe unofarira chigadzirwa chedu, isu tinoshanduka pamwe neyakagadziriswa yemirairo kuti ikwane yako chaiyo yekuda uye yedu yekukurumidza kutungamira nguva pamirairo inovimbisa kuti uchave nekuravira kwedu kukuru chigadzirwa pane-nguva. Isu tinotarisawo pamabasa akawedzerwa-kukosha. Isu tinowanikwa yemibvunzo yebasa uye ruzivo rwekutsigira rako bhizinesi.

Isu tiri nyanzvi yeAlf GPC poda inopa kwemakore akati wandei, tinopa zvigadzirwa nemutengo unokwikwidzana, uye chigadzirwa chedu ndechemhando yepamusoro uye chinoedzwa zvakanyanya, chakazvimirira pakuyedza kuti ive yakachengeteka kuti ishandiswe pasi rese.

References

  • Ricci A, Bronzetti E, Vega JA, Amenta F. Oral choline alfoscerate anopikisa zera-inotsamira kurasikirwa kwemasuru mousy muchero hippocampus. Mech Kukweguru Dev. 1992; 66 (1): 81-91. PubMed PMID: 1340517.
  • Amenta F, Ferrante F, Vega JA, Zaccheo D. Nguva refu choline alfoscerate kurapwa kunoenderana nezera-inotsamira microanatomical shanduko mune rat brain. Prog Neuropsychopharmacol Biol Psychiatry. 1994 Sep; 18 (5): 915-24. PubMed PMID: 7972861.
  • Amenta F, Del Valle M, Vega JA, Zaccheo D. Age-inoenderana nekushanduka kwechimiro mune rat cerebellar cortex: mhedzisiro ye choline alfoscerate kurapwa. Mech Kukweguru Dev. 1991 Zvita 2; 61 (2): 173-86. PubMed PMID: 1824122.