Palmitoylethanolamide (Pea) (544-31-0)

Palmitoylethanolamide (PEA) (544-31-0) vhidhiyo

Palmitoylethanolamide (Pea) Specifications

Chii chinonzi Palmitoylethanolamide (544-31-0)?

Palmitoylethanolamide (PEA), an endo native (inogadzirwa nemuviri) fatty acid amide, iri kubuda semubatsiri mutsva mukurapa maronda uye kuzvimba. Seyese endo native agent uye imwe zvakare inowanikwa mune zvekudya senge mazai uye mukaka, hapana zvakakomba mhedzisiro kana kubatana kwezvinodhaka-zvinodhaka zvakaonekwa. PEA yakaratidza kushanda kwekurwara kusingaperi kwemararamiro akawanda ane hukama nemamiriro ezvinhu mazhinji anorwadza, kunyanya neropathicic (nerve) kurwadziwa, kurwadziwa kwepadumbu uye kurwadziwa kwemaziso sekunge endometriosis uye interstitial cystitis.

Palmitoylethanolamide (544-31-0) zvakanaka

Pakutanga, iyo inoderedza, kuburikidza neiyo peroxisome proliferator-activated receptor alpha (PPARα), kutora uye kuvandudza kwemaseru masero kunzvimbo dzekurwadziwa kweropa uye kusunungurwa kwevanomukira-vapesanisi vemasvikiro kubva kumasero aya; kechipiri, inodzivirira iyo micoglia activation uye kutora nhengo dzemast seli mukati memuzongoza mushure mekukuvara kwemutsipa wepelinha, pamwe nekutevera kumusana neuroinfigueation kana kukuvara kwemuzongoza.

Ongororo dzinoverengeka dzakatarisana nekushandiswa kwePMA mune yakawanda yemamiriro ekurwadziwa kusingaperi. Semuenzaniso, inogona kuve nemhedzisiro inobatsira senge inodhaka pakurapa kweanodzokera kurwadziwa kana yakashandiswa yega kurapwa kwekurwadziwa kwemarwere mune varwere vakanyanya vanorwara, uko kushandiswa kwemaitiro analgesics kunogona kukonzera njodzi yakanyanya yekunetsa. Mhedzisiro inokurudzira yakaratidzwa mukurapa kwevasina-kuvhiyiwa radiculopathies neine Ultra-micronized kuumbwa kwe PEA uye iyo yekurapa yekurapa nealpha-lipoic acid kuderedza chirwere chepratitis / chisingaperi pelvic pain syndrome.

Palmitoylethanolamide (544-31-0) Mechanism Yekuita?

Palmitoylethanolamide (PEA) is endogenous fatty acid amide, analog ye endocannabinoid anandamide (AEA), iyo ndeye yemhuri yeN-acylethanolamines (NAE). NAEs inoburitswa kubva kumasero mukupindura noxious kukurudzira. Sezvese maEEE, zvakare PEA ine maitiro emuno, uye huwandu hwayo hwematoni hwakanyatsorongeka kuburikidza nehuremu hwekugadzira uye kushatisa basa. Mairi maviri e-intracellular amidases, anoratidzwa mumasokisi anokanganisa, akabatanidzwa mukuparadzwa kwe lipid amide: fatty-acid amide hydrolase (FAAH) uye N-acylethanolamine hydrolyzing acid amidase (NAAA).

Palmitoylethanolamide (544-31-0) kunyoresa

Palmitoylethanolamide (PEA) ndezve endocannabinoid mhuri, boka remafuta acid amides. PEA yakaratidzwa kuve ine analgesic uye yekudzivirira-kuita basa uye yakashandiswa mune dzinoverengeka kudzidziswa zvidzidzo zvakanangana nekutarisira kwekusingaperi kurwadziwa pakati pevarwere vakura vane zvakasiyana zvinokonzerwa nekiriniki mamiriro.

Palmitoylethanolamide (Pea) powder Sale(Iko Kutenga Palmitoylethanolamide (PEA) poda muhuwandu)

Kambani yedu inonakidzwa nehurefu hwehukama nevatengi vedu nekuti tinotarisa pakubata kwevatengi nekupa zvigadzirwa zvikuru. Kana iwe unofarira chigadzirwa chedu, isu tinoshanduka pamwe neyakagadziriswa yemirairo kuti ikwane yako chaiyo yekuda uye yedu yekukurumidza kutungamira nguva pamirairo inovimbisa kuti uchave nekuravira kwedu kukuru chigadzirwa pane-nguva. Isu tinotarisawo pamabasa akawedzerwa-kukosha. Isu tinowanikwa yemibvunzo yebasa uye ruzivo rwekutsigira rako bhizinesi.

Isu tiri nyanzvi Palmitoylethanolamide (PEA) poda mutengesi wemakore akati wandei, isu tinopa zvigadzirwa nemakwikwi emutengo, uye chigadzirwa chedu chemhando yepamusoro uye chinoedzwa chakasimba, chakazvimirira bvunzo kuyedza kuti ive yakachengeteka kuti ishandiswe pasi rese.

References

• Hansen HS. Palmitoylethanolamide uye mamwe maamamide congeners. Basa rakarongwa muurwere huchirwara. Expur Neurol. 2010; 224 (1): 48-55
• Petrosino S, Iuvone T, Di Marzo V. N-Palmitoyl-ethanolamine: biochemistry nemikana mitsva yekurapa. Biochimie. 2010; 92 (6): 724–7
• Cerrato S, Brazis P, della Valle MF, Miolo A, Puigdemont A. Mhedzisiro ye Palmitoylethanolamide pane immunologically induction histamine, PGD2 uye TNFα kusunungurwa kubva kune canine ganda mitezo masero. Vet Immunol Immunopathol. 2010; 133 (1): 9–15
• Palmitoylethanolamide (PEA): Zvakanakira, Dosage, Usees, Wedzera