Vinpocetine upfu

November 5, 2020

Cofttek ndiyo yakanakisa Vinpocetine poda inogadzira muChina. Fekitori yedu ine yakakwana yekugadzira manejimendi system (ISO9001 & ISO14001), iine pamwedzi yekugadzira inokwana 340kg.

Mamiriro: MuMitambo Yokugadzira
Unit: 1kg / bhegi, 25kg / Drum

Vinpocetine upfu Specifications

Name: Vinpocetine
CAS: 42971-09-5
Purity 98%
Molecular Formula: C22H26N2O2
Molecular Kurema: 350.454 g / mol
Melt Point: 147-149 ° C
Kemikari zita: AY-27255, Cavinton, Eburnamenine-14-carboxylic acid, Ethyl Apovincaminate, Ethylapovincaminoate,
Synonyms: Ethyl Ester, RGH-4405, TCV-3b, Vinpocetin, Vinpocetina, Vinpocétine.
InChI Key: DDNCQMVWWZOMLN-IRLDBZIGSA-N
Kubvisa Hafu Hupenyu: 2.54 +/- 0.48 maawa
Solubility: Soluble muDMSO, Methanol, Mvura
Chengetedzo Chimiro: 0 - 4 C kwenguva pfupi (mazuva kusvika kumavhiki), kana -20 C kwenguva refu (mwedzi)
Application: Vinpocetine mubatanidzwa unobva pachirimwa chePeriwinkle icho chinoshandiswa sechirevo chekuziva uye chekudzivirira kuchembera. Imwe yeanowanzozivikanwa ma nootropics, Vinpocetine inogona kuwedzera kuyerera kweropa uye inoitirwa kuwedzera ndangariro; ichi chekupedzisira chirevo hachina kuongororwa.
Kuonekwa: White powder

 

Vinpocetine (42971-09-5) NMR Spectrum

Vinpocetine (42971-09-5) - NMR Spectrum

Kana iwe uchida COA, MSDS, HNMR kune rimwe nerimwe batch yechigadzirwa uye rumwe ruzivo, ndapota nyorera vedu mutengesi wekushambadzira.

 

Chii chinonzi Vinpocetine (42971-09-5)?

Vinpocetine inogadzirwa alkaloid yakatorwa kubva periwinkle chirimwa (kunyanya, chakagadzirwa kubva mumorekuru rinozivikanwa se 'vincamine') inoita kunge ine track rekodhi yekushandisa munyika dzeEuropean pakurapa kwekuziva kwekudzikira, kupora sitiroko, uye pfari. Vinpocetine zvakare inowanzo shandiswa sechinhu che nootropic mune tarisiro yekuti inogona kukurudzira ndangariro kugadzirwa.

 

Vinpocetine powder (42971-09-5) mabhenefiti

Vinpocetine haina kunyura zvakazara, asi izvo zvinonwiwa zvinokwira muropa nekukurumidza uye nyore zvinopinda muuropi mainogona kushandisa mashandiro ayo. Izvo zvinhu zvinoita senge zvinoshanda kumuromo vinpocetine yekuwedzera inosanganisira neuroprotection (inopesana nehupfu uye yakawandisa kukurudzira) uye kudzikisira neural kuzvimba, nepo kugona kwekuziva kwekusimudzira kuchiratidzika kunge kusingatsigirike nehumbowo panguva ino nenguva. Nepo vinpocetine ichiita senge inoshanda mukudzivirira chepfu kana kushungurudzika kubva mukukonzera amnesia, haisati yaratidzirwa kuti inowedzeredza kuvandudza ndangariro.

Vinpocetine inoitawo kunge iine hunyanzvi pakurwisa kudzikira, asi huwandu hwezvinyorwa pamusoro penyaya iyi hwakanyanya kushoma pane mimwe mishonga yakaedzwa pachinangwa ichi (CDP-Choline kana Alpha-GPC kunyanya). Chidzidzo chimwe chete chakacherekedza kuvandudzwa kwekuita nguva neine 40mg piritsi revinpocetine, inogona kuve imwe yeanongoitika akakodzera kuvandudza kune vanhu vane hutano panguva ino munguva.

Kufuridzirwa kwevinpocetine kunoonekwa kunowedzera kuyerera kweropa kuenda kuuropi pasina maitiro ekugadzirisa kumanikidza, uye izvi zvinofungidzirwa (asi hazviratidzwe) kunyorera mukumwa kwemumuromo. Izvi zvingangoderedza kutemwa nemusoro kunokonzerwa nekumanikidza kwakanyanya, uye zvinoenderana nekushandisa kwetsika kweperiwinkle chirimwa (kudzora kutemwa nemusoro).

 

Vinpocetine (42971-09-5) kunyoresa?

Maitiro e vinpocetine akawanda. Inoita kunge inofambidzana nenzira dzinoverengeka dzeion (sodium, potasium, uye calcium) painenge ichitungamira mukukonzeresa mhedzisiro pakuburitswa kweiyo neurotransmitter uye neuroprotection kana dopamine kana glutamate yakadzvanywa (izvi zviviri, kana zvisina kufanira zvichikurudzirwa nehupfu, zvinogona kukonzera kukuvara kweiyo oxidative). Iyo zvakare inopindirana ne alpha adrenergic receptors uye iyo TPSO receptor, uye nepo kubatsirwa chaiko kweiyi yekudyidzana kusangana kusiri kujekesa kuti ingangove yakakosha sezvo ichiitika pakumatanho kumwe chete kunoitwa neon chiteshi kusangana.

Vinpocetine zvakare iri PDE1 inhibitor, inova nzira iyo iri mbiri cardioprotective uye kugona kugadzirisa. Nehurombo, ichi chinodzivirira chinoitika padosi yakakura chaizvo uye chingasashande kune akajairwa ekuwedzera madosi evinpocetine.

Zvakafanana ne PDE1, antidopaminergic kugona kwevinpocetine uye yakanangana nekudzivirira kwe glutaminergic receptors zvese zvinoita kunge zvinoitika pakukwirira kwakanyanya mu vitro uye zvinogona kunge zvisina basa kune yakajairwa yekuwedzera.

 

Vinpocetine (42971-09-5) Dosage

Vinpocetine inotorwa mumayero ezuva nezuva e15-60mg, yakakamurwa kuita matatu ezvezuva nezuva nemadyo. Iyo yakadzika yakaderera dosi ndeye 5mg pane imwe yeizvi zvitatu zvekudya, iine 20mg pakudya kwese kuchionekwa semhedzisiro yepamusoro yekubudirira. Aya madosi anotorwa kuitira zvinangwa zveuroprotection, kusimudzira cerebral kuyerera kweropa, uye kudzikisa chiyero chekuziva kwekudzikira.

Maitiro mumucheto wepamusoro weiyo renji (30-45mg acute madosi) inogona kubatsira kusimudzira kugona uye ndangariro kuumbwa mune vamwe vanhu vane hutano, asi hapana humbowo hwakawanda hwakatarisa uku kutaura.

Yambiro: kune vakadzi vane nhumbu, iyo yakaenzana yedosi inovhura 10 mg / d yakabatanidzwa kune fetal chepfu muzvidzidzo zvemhuka. 10 mg / d inogona zvakare kuve ine njodzi, kunyanya kana uchitora mukati mese kubata pamuviri.

 

Vinpocetine powder Sale(Kwokutenga Vinpocetine poda yakawanda)

Kambani yedu inonakidzwa nehurefu hwehukama nevatengi vedu nekuti tinotarisa pakubata kwevatengi nekupa zvigadzirwa zvikuru. Kana iwe unofarira chigadzirwa chedu, isu tinoshanduka pamwe neyakagadziriswa yemirairo kuti ikwane yako chaiyo yekuda uye yedu yekukurumidza kutungamira nguva pamirairo inovimbisa kuti uchave nekuravira kwedu kukuru chigadzirwa pane-nguva. Isu tinotarisawo pamabasa akawedzerwa-kukosha. Isu tinowanikwa yemibvunzo yebasa uye ruzivo rwekutsigira rako bhizinesi.

Isu tiri nyanzvi Vinpocetine poda mupi wekutengesa kwemakore akati wandei, isu tinopa zvigadzirwa nemakwikwi mutengo, uye chigadzirwa chedu chiri chemhando yepamusoro uye chinoenda kuomarara, kuyedza yakazvimirira kuona kuti yakachengeteka kudyiwa pasirese.

 

References
  1. Abdel-Salam OME. Vinpocetine uye piracetam inoshandisa antinociceptive maitiro mune visceral pain modhi mumakonzo Pharmacol Rep. 2006; 58 (5): 680-691.17085860
  2. Akopov SE, Gabrielian ES. Mhedzisiro yeasipurini, dipyridamole, nifedipine uye Cavinton iyo inoshanda pane platelet kuunganidzwa kunokonzerwa neakasiyana ekumisikidza vamiririri voga uye musanganiswa. Eur J Kliniki Pharmacol. 1992; 42 (3): 257-259.1577042
  3. Alkuraishy HM, Al-Gareeb AI, Albuhadilly AK. Vinpocetine uye pyritinol: mhando nyowani yeropa rheological modulation mune cerebrovascular kusagadzikana-yakarongeka inodzorwa kiriniki kudzidza. Biomed Res Int. 2014; 2014: 324307.25548768.